Chief Executive Officer
Mr. Lappe co-founded Inhibrx in 2010 and has served as our Chief Executive Officer and Chief Financial Officer since our inception. Mark also serves as the Chairman of our board of directors. Mr. Lappe has extensive expertise in the biotechnology industry with over thirty years of experience in executive management, investment management and executive recruiting, having built the executive teams of over forty start-up biotechnology and medical device companies. Prior to founding Inhibrx, Mr. Lappe was the founder and Managing Partner of Efficacy Biotech Fund, a fund focused on strategic investment in public biotechnology companies. We believe Mr. Lappe’s service as our co-founder and Chief Executive Officer and his extensive experience in the biotechnology and biotherapeutic industries qualifies him to serve on our board of directors.
EVP Corporate Strategy
Dr. Eckelman co-founded Inhibrx in April 2010 and currently serves as our Chief Scientific Officer and Executive Vice President of Corporate Strategy. From August 2015 to November 2018 Dr. Eckelman served as our Chief Operating Officer and Vice President of Biotherapeutics. From 2010 until August 2015, Dr. Eckelman served as our Vice President of Scientific Operations. Dr. Eckelman has served as a member of our Board of Directors since April 2018. Dr. Eckelman is head of our research team, overseeing several key functional areas spanning discovery to therapeutic development. In addition, he has critical responsibilities in corporate strategy and operations. Prior to co-founding Inhibrx, Dr. Eckelman was a Research Investigator in the biotherapeutics group at the Genomics Institute of the Novartis Research Foundation. Dr. Eckelman conducted his graduate research at the Sanford-Burnham-Prebys Medical Discovery Institute and received Ph.D. in Molecular Pathology from the University of California, San Diego, or UCSD, School of Medicine. Dr. Eckelman received his B.S. in Molecular Biology and his M.S. in Biology from UCSD. We believe Dr. Eckelman is qualified to serve on our board of directors because of his extensive operational business experience, significant knowledge of the activities of our company, including his experience as one of our co-founders and various leadership roles within the company including Chief Scientific Officer and Chief Operating Officer, as well as his experience developing protein therapeutic candidates and biotherapeutic product candidates.
EVP Early Research
A co-founder of Inhibrx, Quinn leads target identification and validation, therapeutic lead selection and oversees the pipeline development strategy. Prior to founding Inhibrx, he spent 10 years at the Genomics Institute of the Novartis Research Foundation (GNF). Quinn led groups of Ph.D./M.D. level investigators in the conception and generation of novel target identification and validation platforms. Quinn was a key member of the team that transitioned the first GNF therapeutic antibody from bench-top to clinical trials. His research on cell death at the Stanford-Burnham-Prebys Medical Discovery Institute has been highly cited. Quinn received his Ph.D. in biochemistry from the University of Utah School of Medicine.
Dr. Wagner has served as our Chief Medical Officer since August 2015 and leads the clinical translation of our biotherapeutic pipeline. From November 2012 until August 2015, Dr. Wagner served as medical oncologist at Banner MD Anderson Cancer Center and as Adjunct Assistant Professor, Department of Thoracic, Head & Neck Medical Oncology at MD Anderson Cancer Center, where he lead cancer immunotherapy trials as the local principal investigator. From July 2009 until September 2011, Dr. Wagner trained at MD Anderson Cancer Center as a fellow in Medical Oncology. Dr. Wagner’s scientific work at Genentech, Inc. and the Genomics Institute of the Novartis Research Foundation focused on drug discovery and predictive biomarker development. Dr. Wagner received the highest academic honors and was a scholar of the German Academic Scholarship Foundation. Dr. Wagner received his M.D. and Ph.D. from the Friedrich-Alexander University of Erlangen in Germany.
Ashraf is responsible for the late stage activities required for commercialization of Inhibrx programs. He brings more than 20 years of experience in process development, technical operations, cGMP clinical manufacturing, commercialization and life cycle management of antibody therapeutics, vaccines, gene therapy, cell-based therapeutics and recombinant proteins. Prior to joining Inhibrx, Ashraf held executive and senior level positions with aTyr Pharma, Gilead Sciences, Genentech, and Merck & Co. Inc. He is the author of 55 peer-reviewed publications and his work has been presented at over 120 conferences. He is on the editorial board of the Biotechnology & Bioengineering and mAb journals. Ashraf received his Ph.D. in Chemical Engineering from The University of Birmingham (UK) and conducted post-doctoral studies with The University of Birmingham, Novo Nordisk, Merck Sharpe & Dohme and University College London.
John leads many aspects of research at Inhibrx, including protein engineering, assay development, and new technologies. He has been instrumental in developing the Inhibrx multi-specific antibody formats for conditional immune activation and generally oversees single domain antibody discovery projects. Prior to joining Inhibrx in 2010, John completed his postdoctoral training in Jack Dixon’s laboratory in the Department of Pharmacology at UCSD. John received his Ph.D. from the UCSD Biomedical Sciences Program, performing his thesis research in the laboratory of Guy Salvesen at the Sanford-Burnham-Prebys Medical Discover Institute.
Analeah leads translational research at Inhibrx and is responsible for non-clinical research in support of multiple IND filings annually. Prior to joining Inhibrx she spent ten years at Novartis in biologics drug discovery in multiple roles from oncology target validation through candidate optimization for varied therapeutic modalities, including antibody drug conjugates and immune activating agents. Analeah received her Ph.D. from the University of California, San Francisco in biochemistry and molecular biology and completed her postdoctoral research at the Genomics Institute for the Novartis Research Foundation.
Stuart leads process development and product manufacturing activities at Inhibrx, including sub-teams for upstream and downstream process development and analytical and formulation development. His team internally produces and characterizes materials for efficacy, PK, and exploratory and GLP toxicology studies and works with contract organizations for the production and release of materials for clinical studies. Prior to joining Inhibrx, Stuart led teams of engineers and scientists developing novel protein production platforms at Sutro Biopharma and Ambrx and worked on experimental growth factor, antibody, and antibody drug conjugate therapies. Stuart received his Ph.D. in chemical engineering from Cornell University.
Kelly leads the accounting and finance team at Inhibrx and is responsible for all internal and external reporting requirements, as well as day-to-day accounting activities. Kelly joined Inhibrx in October 2018, bringing with her over 15 years of experience in the life science industry. Prior to joining Inhibrx, Kelly held various accounting and finance positions of increasing responsibility with Apricus Biosciences, Inc., Hologic Inc., Gen-Probe, Inc., and Cytori Therapeutics, Inc. Kelly has a B.S. and M.S. in Accounting and is an active licensed Certified Public Accountant in the state of California.
Leah serves as the General Counsel of Inhibrx and manages the Company’s legal affairs. Prior to joining Inhibrx, she spent ten years in private law practice with two large full service law firms where she counseled both public and private companies in a range of transactional and corporate matters, with a focus on mergers and acquisitions, venture capital financings, corporate governance, and general corporate matters. Leah received her Juris Doctor degree from the University of Missouri-Kansas City School of Law.
Kirsti leads clinical operations at Inhibrx and is responsible for internal and external teams executing Inhibrx’s clinical studies. Prior to joining Inhibrx, Kirsti spent six years as an independent research consultant providing expertise, leadership and hands-on support for all phases of drug development. She worked with small biotech start-ups and mid-size pharmaceutical companies in clinical development, operational strategy, and quality assurance cumulating in several successful NDAs. For eleven years prior, Kirsti held several positions of increasing responsibility managing clinical studies in the biotech industry and at the University of California San Diego, School of Medicine. Kirsti has extensive global clinical trials experience in multiple therapeutic areas. She received her M.A. in Experimental Psychology.