Ozekibart (INBRX-109) Phase 2 Trial

Phase 2 placebo-controlled randomized study of the tetravalent DR5 agonist ozekibart (INBRX-109) in patients with unresectable or metastatic conventional chondrosarcoma.

ClinicalTrials.gov
Ozekibart Chart

Key Eligibility Criteria:

+ Conventional chondrosarcoma, unresectable or metastatic
+ Available archival tissue or fresh tumor biopsy
+ Radiographic progression per RECIST 1.1 within 6 months of study treatment initiation
+ Adequate hepatic function
+ No chronic liver diseases; Exception: Patients with fatty liver disease are acceptable as long as adequate hepatic function as defined in the inclusion/exclusion criteria is confirmed
+ No clinically significant or uncontrolled comorbidities

Click on the interactive world map to view where this study is currently enrolling patients.