Inhibrx and 2seventy bio, formerly known as bluebird bio, began a research collaboration in 2016. Since that time, the collaboration has focused on researching, developing,and commercializing chimeric antigen receptor (CAR) T-cell therapies using Inhibrx’s proprietary single-domain antibody (sdAb) platform to multiple cancer targets.

• In 2018, Inhibrx granted 2seventy worldwide rights to develop, manufacture, and commercialize certain cell therapy products.
• In 2020, Inhibrx granted 2seventy exclusive worldwide rights to develop binders and cell therapy products containing sdAbs directed to specified targets for two programs and up to an additional eight programs.

In June 2012, Inhibrx and Celgene, now a Bristol-Myers Squibb Company, entered into a Development and Option agreement related to our CD47 checkpoint inhibitor.

In July 2013, Celgene opted to exercise its option and was granted an exclusive global license for the development, manufacture, and commercialization of our proprietary CD47 binding domain.

In 2015, Inhibrx and the Alpha-1 Foundation began a collaboration to develop a recombinant alpha-1 antitrypsin therapeutic with improved properties, INBRX-101.